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Targeted Protein Degradation
NATURE REVIEWS: CLINICAL ONCOLOGY
Protein degraders enter the clinic — a new approach to cancer therapy
BIOCHEMISTRYMolecular Glues: The Adhesive Connecting Targeted Protein Degradation to the Clinic
NATURE REVIEWS: DRUG DISCOVERYTargeted protein degraders crowd into the clinic
NATURE CHEMICAL BIOLOGYMolecular glue concept solidifies
LSD1’s Role in Cancer
National Library of Medicine
Roles of lysine-specific demethylase 1 (LSD1) in homeostasis and diseases
Nature ImmunologyHistone demethylase LSD1 is required for germinal center formation and BCL6-driven lymphomagenesis
CellLSD1 Ablation Stimulates Anti-tumor Immunity and Enables Checkpoint Blockade
ACS chemical biologyLysine-specific histone demethylase 1 inhibitors control breast cancer proliferation in ERα-dependent and-independent manners.
SP-2577 and Analogs
National Library of Medicine